| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NIDE1893 | NIDE1894 | NIDE1893 | NIDE1894 | Putative RNA methylase, UPF0020; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. | Putative Nudix hydrolase, MutT family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the Nudix hydrolase family. | 0.618 |
| NIDE1893 | nusA | NIDE1893 | NIDE4134 | Putative RNA methylase, UPF0020; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | 0.473 |
| NIDE1893 | otsA2 | NIDE1893 | NIDE1892 | Putative RNA methylase, UPF0020; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. | Alpha,alpha-trehalose-phosphate synthase (UDP-forming); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.452 |
| NIDE1893 | pnp | NIDE1893 | NIDE4127 | Putative RNA methylase, UPF0020; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.715 |
| NIDE1893 | pyrG | NIDE1893 | NIDE2555 | Putative RNA methylase, UPF0020; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.666 |
| NIDE1893 | ribD | NIDE1893 | NIDE1635 | Putative RNA methylase, UPF0020; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. | Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.488 |
| NIDE1893 | rimM | NIDE1893 | NIDE3072 | Putative RNA methylase, UPF0020; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. | Ribosome maturation factor RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | 0.548 |
| NIDE1893 | trmFO | NIDE1893 | NIDE0295 | Putative RNA methylase, UPF0020; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. | tRNA uridine 5-carboxymethylaminomethyl modification enzyme gid; Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs; Belongs to the MnmG family. TrmFO subfamily. | 0.656 |
| NIDE1893 | uppS | NIDE1893 | NIDE1513 | Putative RNA methylase, UPF0020; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. | Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.755 |
| NIDE1893 | yhbC | NIDE1893 | NIDE4135 | Putative RNA methylase, UPF0020; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. | Conserved protein of unknown function DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | 0.475 |
| NIDE1894 | NIDE1893 | NIDE1894 | NIDE1893 | Putative Nudix hydrolase, MutT family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the Nudix hydrolase family. | Putative RNA methylase, UPF0020; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. | 0.618 |
| nusA | NIDE1893 | NIDE4134 | NIDE1893 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | Putative RNA methylase, UPF0020; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. | 0.473 |
| nusA | pnp | NIDE4134 | NIDE4127 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | 0.960 |
| nusA | pyrG | NIDE4134 | NIDE2555 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | CTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.727 |
| nusA | rimM | NIDE4134 | NIDE3072 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | Ribosome maturation factor RimM; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. | 0.846 |
| nusA | uppS | NIDE4134 | NIDE1513 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.815 |
| nusA | yhbC | NIDE4134 | NIDE4135 | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | Conserved protein of unknown function DUF150; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. | 0.971 |
| otsA2 | NIDE1893 | NIDE1892 | NIDE1893 | Alpha,alpha-trehalose-phosphate synthase (UDP-forming); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative RNA methylase, UPF0020; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. | 0.452 |
| pnp | NIDE1893 | NIDE4127 | NIDE1893 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Putative RNA methylase, UPF0020; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the methyltransferase superfamily. | 0.715 |
| pnp | nusA | NIDE4127 | NIDE4134 | Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. | Transcription termination factor NusA; Participates in both transcription termination and antitermination. | 0.960 |