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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE1901Putative Type I restriction system, restriction protein HsdR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (1007 aa)    
Predicted Functional Partners:
NIDE1898
Putative Type I restriction system, N-6 adenine-specific DNA methylase HsdM; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.961
NIDE1900
Putative Type I restriction system, specificity protein HsdS; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
 
  
 0.946
NIDE2502
Putative Type I restriction-modification system, N-6 adenine-specific DNA methylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.936
NIDE2503
Putative Type I restriction-modification system, specificity protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
 
  
 0.913
hsdM
Type I restriction endonuclease, M subunit (modular protein); Function of strongly homologous gene; enzyme.
 
 
 0.776
NIDE2146
Protein of unknown function; No homology to any previously reported sequences.
  
 
 0.730
hsdM2
Type I restriction-modification system, methyltransferase subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.730
NIDE3670
DNA modification methylase; Function of strongly homologous gene; enzyme.
  
 
 0.730
NIDE2623
Conserved protein of unknown function, RhuM family; Homologs of previously reported genes of unknown function; 9922266.
  
    0.681
NIDE0137
Protein of unknown function, putative Type I restriction endonuclease, S subunit; No homology to any previously reported sequences.
  
  
 0.631
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.