Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
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NIDE1906Putative Metallophosphoesterase, possible DNA repair exonuclease SbcCD, subunit D; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (419 aa)    
Predicted Functional Partners:
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
  
 0.987
NIDE1907
Conserved protein of unknown function, putative DNA repair exonuclease SbcCD, subunit C; Homologs of previously reported genes of unknown function; 9133662, 9242643, 9653124, 9927737.
 
 
 0.956
recQ
ATP-dependent DNA helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.902
recA
Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 0.878
NIDE0128
Putative DEAD/DEAH box helicase, SNF2 family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.851
NIDE1291
ATP-dependent DNA helicase; Function of strongly homologous gene; enzyme.
   
 
 0.813
top6A
DNA topoisomerase VI, subunit A; Relaxes both positive and negative superturns and exhibits a strong decatenase activity; Belongs to the TOP6A family.
   
 0.813
NIDE1875
Probable Peroxiredoxin; Function of strongly homologous gene; enzyme.
  
 
 0.726
NIDE0899
Putative Quinol-cytochrome c reductase, cytochrome b subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative carrier.
    
 
 0.716
qcrB
Quinol-cytochrome c reductase, fused cytochrome b/c subunit; Function of strongly homologous gene; carrier.
    
 
 0.716
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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