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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
clpV1Type VI secretion ATPase, ClpV1 family; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ClpA/ClpB family. (909 aa)    
Predicted Functional Partners:
NIDE2011
Homologs of previously reported genes of unknown function.
 
 0.969
NIDE1984
Conserved protein of unknown function, COG3520; Homologs of previously reported genes of unknown function; 16763151, 19284603.
 
  
 0.950
clpP
ATP-dependent Clp protease, proteolytic subunit clpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family.
 
 
 0.945
NIDE1983
Conserved protein of unknown function, COG3519; Homologs of previously reported genes of unknown function; 16763151, 19284603.
 
  
 0.945
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.943
hscA
Chaperone protein HscA (Hsc66); Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the heat shock protein 70 family.
  
 
 0.943
NIDE1982
Conserved protein of unknown function, COG3518; Homologs of previously reported genes of unknown function; 3520236, 19284603.
 
  
 0.937
NIDE1987
Conserved protein of unknown function, Rhs element Vgr protein family; Homologs of previously reported genes of unknown function; 16763151, 9696756, 19284603.
 
  
 0.924
NIDE1978
Conserved protein of unknown function, COG3517; Homologs of previously reported genes of unknown function; 16763151, 8573354, 19284603.
 
 0.911
clpS
ATP-dependent Clp protease adapter protein ClpS; Function of strongly homologous gene; regulator; Belongs to the ClpS family.
  
 
 0.879
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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