| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aroC | pabB | NIDE1426 | NIDE3736 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Aminodeoxychorismate synthase, component I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.904 |
| aroC | pheA | NIDE1426 | NIDE0419 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | P-protein, bifunctional chorismate mutase/prephenate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.989 |
| aroC | trpA | NIDE1426 | NIDE2047 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.785 |
| aroC | trpB | NIDE1426 | NIDE2046 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.589 |
| aroC | trpD | NIDE1426 | NIDE0409 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate phosphoribosyltransferase; Function of strongly homologous gene; enzyme. | 0.454 |
| aroC | trpD-2 | NIDE1426 | NIDE2042 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.454 |
| aroC | trpE | NIDE1426 | NIDE2040 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.945 |
| aroC | trpG | NIDE1426 | NIDE2041 | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Anthranilate synthase, component II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.904 |
| pabB | aroC | NIDE3736 | NIDE1426 | Aminodeoxychorismate synthase, component I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.904 |
| pabB | pheA | NIDE3736 | NIDE0419 | Aminodeoxychorismate synthase, component I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | P-protein, bifunctional chorismate mutase/prephenate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.898 |
| pabB | trpA | NIDE3736 | NIDE2047 | Aminodeoxychorismate synthase, component I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Tryptophan synthase, alpha subunit; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.939 |
| pabB | trpB | NIDE3736 | NIDE2046 | Aminodeoxychorismate synthase, component I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Tryptophan synthase, beta subunit; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.890 |
| pabB | trpC | NIDE3736 | NIDE2043 | Aminodeoxychorismate synthase, component I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Indole-3-glycerol phosphate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpC family. | 0.995 |
| pabB | trpD | NIDE3736 | NIDE0409 | Aminodeoxychorismate synthase, component I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Anthranilate phosphoribosyltransferase; Function of strongly homologous gene; enzyme. | 0.988 |
| pabB | trpD-2 | NIDE3736 | NIDE2042 | Aminodeoxychorismate synthase, component I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.991 |
| pabB | trpE | NIDE3736 | NIDE2040 | Aminodeoxychorismate synthase, component I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Anthranilate synthase, component I; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concent [...] | 0.820 |
| pabB | trpF | NIDE3736 | NIDE2045 | Aminodeoxychorismate synthase, component I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | N-(5'-phosphoribosyl)anthranilate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpF family. | 0.941 |
| pabB | trpG | NIDE3736 | NIDE2041 | Aminodeoxychorismate synthase, component I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Anthranilate synthase, component II; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.999 |
| pheA | aroC | NIDE0419 | NIDE1426 | P-protein, bifunctional chorismate mutase/prephenate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.989 |
| pheA | pabB | NIDE0419 | NIDE3736 | P-protein, bifunctional chorismate mutase/prephenate dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Aminodeoxychorismate synthase, component I; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.898 |
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