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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cbiXSirohydrochlorin cobaltochelatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. (393 aa)    
Predicted Functional Partners:
cobI
Precorrin-2 C(20)-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the precorrin methyltransferase family.
 
  
 0.994
cobH
Precorrin-8X methylmutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 0.993
cobJ
Precorrin-3B C(17)-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 0.990
cbiD
Putative Cobalt-precorrin-6A synthase [deacetylating]; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
   
 0.986
cbiG
Cobalamin biosynthesis protein CbiG; Function of strongly homologous gene; enzyme.
 
   
 0.983
NIDE2764
Putative Precorrin-2 dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.977
cobA/hemD
Uroporphyrinogen-III C-methyltransferase and Uroporphyrinogen-III synthase (modular protein); Function of strongly homologous gene; enzyme; Belongs to the precorrin methyltransferase family.
 
  
 0.965
cobL
Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
   
 0.963
hemD
Porphyrin biosynthesis protein HemD; Function of strongly homologous gene; enzyme.
 
  
 0.935
cobM
Precorrin-4 C(11)-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
   
 0.923
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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