Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE2106Putative High-affinity nickel/cobalt transport protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the NiCoT transporter (TC 2.A.52) family. (267 aa)    
Predicted Functional Partners:
NIDE3744
Putative Acid phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
     0.671
cobB
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
       0.660
cobL
Precorrin-6Y C(5,15)-methyltransferase (decarboxylating); Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.554
cbiX
Sirohydrochlorin cobaltochelatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.527
cobH
Precorrin-8X methylmutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
    0.513
cobM
Precorrin-4 C(11)-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
       0.510
cobA/hemD
Uroporphyrinogen-III C-methyltransferase and Uroporphyrinogen-III synthase (modular protein); Function of strongly homologous gene; enzyme; Belongs to the precorrin methyltransferase family.
       0.508
cbiD
Putative Cobalt-precorrin-6A synthase [deacetylating]; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
       0.505
cobI
Precorrin-2 C(20)-methyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the precorrin methyltransferase family.
       0.505
cbiG
Cobalamin biosynthesis protein CbiG; Function of strongly homologous gene; enzyme.
       0.505
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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