Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
tadCPilus assembly protein TadC; Function of strongly homologous gene; transporter. (318 aa)    
Predicted Functional Partners:
tadB
Pilus assembly protein TadB; Function of strongly homologous gene; transporter.
 
 
 0.999
cpaF
Pilus assembly ATPase CpaF; Function of strongly homologous gene; enzyme.
 
 
 0.998
NIDE2112
Putative Pilus assembly ATPase CpaE; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.997
cpaB
Pilus assembly protein CpaB (modular protein); Function of strongly homologous gene; structure.
 
 
 0.996
NIDE2116
Putative Pilus assembly protein CpaC; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure; Belongs to the bacterial secretin family.
 
 
 0.992
NIDE2114
Conserved protein of unknown function, TadE-like; Homologs of previously reported genes of unknown function.
 
    0.944
NIDE2113
Homologs of previously reported genes of unknown function.
 
     0.855
NIDE2118
Putative Prepilin peptidase CpaA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
     0.832
tatC
Sec-independent protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes.
      
 0.742
tatC-2
Twin-arginine targeting protein translocase TatC; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes.
      
 0.742
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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