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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE2120Anti-sigma factor antagonist; Function of strongly homologous gene; regulator. (100 aa)    
Predicted Functional Partners:
NIDE2119
Putative Histidine kinase with protein phosphatase region; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
 0.998
NIDE2368
Putative Anti-sigma factor antagonist; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the anti-sigma-factor antagonist family.
  
  
  0.972
flgM
Anti-sigma 28 factor FlgM; Function of homologous gene experimentally demonstrated in an other organism; regulator.
     
  0.900
NIDE0805
Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.853
NIDE0815
Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.853
yrbF
ABC transporter, ATPase component, putative ATP-dependent toluene efflux transporter; Function of strongly homologous gene; enzyme.
   
   0.807
NIDE1504
Putative ABC transporter, ATPase component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
   
   0.807
NIDE3908
Putative ABC-type transport system, ATP binding component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
   
   0.807
NIDE1046
Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.801
NIDE2323
Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 0.801
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.