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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE2126DNA-binding transcriptional regulator, tetR-type; Function of strongly homologous gene; factor. (205 aa)    
Predicted Functional Partners:
NIDE2130
Conserved protein of unknown function, Carboxymuconolactone decarboxylase family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
  
 0.813
NIDE2128
Homologs of previously reported genes of unknown function.
 
     0.617
pth
Aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
    0.589
NIDE2795
Transcriptional regulator, AraC family; Function of strongly homologous gene; regulator.
  
   
 0.553
NIDE3826
Putative CoA-substrate-specific enzyme activase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
     
 0.528
NIDE2127
Putative Short-chain dehydrogenase/reductase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.494
NIDE2796
Transcriptional regulator, AraC family; Function of strongly homologous gene; regulator.
  
   
 0.492
NIDE1185
Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.468
NIDE2190
Putative HTH-type transcriptional regulator, AraC family (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
   
 0.459
NIDE2803
Transcriptional regulator, LysR family; Function of strongly homologous gene; regulator; Belongs to the LysR transcriptional regulatory family.
  
 
 
 0.457
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.