Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE2126DNA-binding transcriptional regulator, tetR-type; Function of strongly homologous gene; factor. (205 aa)    
Predicted Functional Partners:
NIDE2130
Conserved protein of unknown function, Carboxymuconolactone decarboxylase family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
  
 0.803
NIDE2128
Homologs of previously reported genes of unknown function.
 
     0.617
pth
Aminoacyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.
  
    0.574
NIDE2795
Transcriptional regulator, AraC family; Function of strongly homologous gene; regulator.
  
   
 0.548
NIDE2127
Putative Short-chain dehydrogenase/reductase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     
 0.491
NIDE2796
Transcriptional regulator, AraC family; Function of strongly homologous gene; regulator.
  
   
 0.487
NIDE2125
Protein of unknown function; No homology to any previously reported sequences.
       0.454
NIDE2190
Putative HTH-type transcriptional regulator, AraC family (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
   
 0.453
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
     
 0.450
NIDE2803
Transcriptional regulator, LysR family; Function of strongly homologous gene; regulator; Belongs to the LysR transcriptional regulatory family.
  
 
 
 0.438
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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