Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NIDE2128Homologs of previously reported genes of unknown function. (155 aa)    
Predicted Functional Partners:
NIDE2127
Putative Short-chain dehydrogenase/reductase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.773
NIDE2130
Conserved protein of unknown function, Carboxymuconolactone decarboxylase family; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
 
   
 0.714
NIDE2129
Exported protein of unknown function; No homology to any previously reported sequences.
       0.693
NIDE2126
DNA-binding transcriptional regulator, tetR-type; Function of strongly homologous gene; factor.
 
     0.617
NIDE1435
Conserved exported protein of unknown function, DUF302; Homologs of previously reported genes of unknown function.
 
     0.463
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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