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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
istB3Insertion sequence IS21 putative ATP-binding protein; Function of strongly homologous gene; extrachromosomal origin. (259 aa)    
Predicted Functional Partners:
NIDE2138
Putative Transposase for insertion sequence element IS21; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin.
  
 0.953
NIDE0583
Conserved membrane protein of unknown function, UPF0114; Homologs of previously reported genes of unknown function.
 
      0.833
dnaB
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
 
 0.828
dnaB-2
Replicative DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
  
 
 0.828
NIDE2837
Putative Transposase for insertion sequence element IS21; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin.
  
 0.808
istA-2
Putative Transposase for insertion sequence element IS21; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin.
  
 0.801
istA
Transposase for insertion sequence element IS21; Function of strongly homologous gene; enzyme.
  
 0.801
NIDE2137
Transposase, IS111A/IS1328/IS1533 family (modular protein); Function of strongly homologous gene; extrachromosomal origin.
       0.773
NIDE2140
Putative Transposase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin.
       0.613
NIDE2135
Putative Transposase related protein (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; extrachromosomal origin.
       0.569
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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