close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE2177Conserved membrane protein of unknown function, contains PepSY-associated TM helices; Homologs of previously reported genes of unknown function; 18511074. (410 aa)    
Predicted Functional Partners:
NIDE0659
TonB-dependent siderophore receptor; Function of strongly homologous gene; receptor.
 
  
 0.783
NIDE0644
TonB-dependent siderophore receptor; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
   
 0.749
NIDE2183
Putative Ferric iron uptake protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
  
 0.744
fhuA
Ferrichrome iron receptor; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
  
 0.734
fecR2
Protein FecR, ferric citrate sensor; Function of strongly homologous gene; regulator.
 
     0.720
fecR
Protein FecR, ferric citrate sensor; Function of strongly homologous gene; regulator.
 
     0.703
NIDE2179
Putative Protein FecR, ferric citrate sensor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
     0.699
NIDE3525
Putative Iron dicitrate transmembrane sensor FecR; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator.
 
     0.696
NIDE2584
Conserved exported protein of unknown function DUF1597; Homologs of previously reported genes of unknown function.
  
     0.692
NIDE2180
Putative RNA polymerase sigma factor FecI (sigma-19); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator; Belongs to the sigma-70 factor family. ECF subfamily.
  
     0.659
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.