NIDE2242 protein (Nitrospira defluvii) - STRING interaction network

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second shell of interactors

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proteins of unknown 3D structure

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Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

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[Homology]

Score

NIDE2242

Homologs of previously reported genes of unknown function. (355 aa)

Predicted Functional Partners:

hemH

0.953

NIDE0561

0.941

NIDE2243

0.773

NIDE4176

0.593

NIDE0206

0.589

forE

0.580

NIDE2245

0.539

hemY

0.519

hemD

0.494

cobA/hemD

0.490

Your Current Organism:

Nitrospira defluvii

NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NIDE0206	NIDE0561	NIDE0206	NIDE0561	Protein of unknown function, CbiX domain; No homology to any previously reported sequences; 11215515, 12055304, 12686546, 12869542, 16042605, 16835730.	Radical SAM superfamily protein, putative Coenzyme PQQ synthesis protein E; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.510
NIDE0206	NIDE2242	NIDE0206	NIDE2242	Protein of unknown function, CbiX domain; No homology to any previously reported sequences; 11215515, 12055304, 12686546, 12869542, 16042605, 16835730.	Homologs of previously reported genes of unknown function.	0.589
NIDE0206	NIDE4176	NIDE0206	NIDE4176	Protein of unknown function, CbiX domain; No homology to any previously reported sequences; 11215515, 12055304, 12686546, 12869542, 16042605, 16835730.	Putative Uroporphyrinogen III synthase HemD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.643
NIDE0206	cobA/hemD	NIDE0206	NIDE2103	Protein of unknown function, CbiX domain; No homology to any previously reported sequences; 11215515, 12055304, 12686546, 12869542, 16042605, 16835730.	Uroporphyrinogen-III C-methyltransferase and Uroporphyrinogen-III synthase (modular protein); Function of strongly homologous gene; enzyme; Belongs to the precorrin methyltransferase family.	0.696
NIDE0206	forE	NIDE0206	NIDE0825	Protein of unknown function, CbiX domain; No homology to any previously reported sequences; 11215515, 12055304, 12686546, 12869542, 16042605, 16835730.	2-oxoglutarate:ferredoxin oxidoreductase epsilon subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.579
NIDE0206	hemD	NIDE0206	NIDE2743	Protein of unknown function, CbiX domain; No homology to any previously reported sequences; 11215515, 12055304, 12686546, 12869542, 16042605, 16835730.	Porphyrin biosynthesis protein HemD; Function of strongly homologous gene; enzyme.	0.695
NIDE0206	hemH	NIDE0206	NIDE1216	Protein of unknown function, CbiX domain; No homology to any previously reported sequences; 11215515, 12055304, 12686546, 12869542, 16042605, 16835730.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.	0.572
NIDE0206	hemY	NIDE0206	NIDE1217	Protein of unknown function, CbiX domain; No homology to any previously reported sequences; 11215515, 12055304, 12686546, 12869542, 16042605, 16835730.	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.	0.547
NIDE0561	NIDE0206	NIDE0561	NIDE0206	Radical SAM superfamily protein, putative Coenzyme PQQ synthesis protein E; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Protein of unknown function, CbiX domain; No homology to any previously reported sequences; 11215515, 12055304, 12686546, 12869542, 16042605, 16835730.	0.510
NIDE0561	NIDE2242	NIDE0561	NIDE2242	Radical SAM superfamily protein, putative Coenzyme PQQ synthesis protein E; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Homologs of previously reported genes of unknown function.	0.941
NIDE0561	NIDE4176	NIDE0561	NIDE4176	Radical SAM superfamily protein, putative Coenzyme PQQ synthesis protein E; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Putative Uroporphyrinogen III synthase HemD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.516
NIDE0561	cobA/hemD	NIDE0561	NIDE2103	Radical SAM superfamily protein, putative Coenzyme PQQ synthesis protein E; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Uroporphyrinogen-III C-methyltransferase and Uroporphyrinogen-III synthase (modular protein); Function of strongly homologous gene; enzyme; Belongs to the precorrin methyltransferase family.	0.582
NIDE0561	forE	NIDE0561	NIDE0825	Radical SAM superfamily protein, putative Coenzyme PQQ synthesis protein E; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	2-oxoglutarate:ferredoxin oxidoreductase epsilon subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.	0.499
NIDE0561	hemD	NIDE0561	NIDE2743	Radical SAM superfamily protein, putative Coenzyme PQQ synthesis protein E; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Porphyrin biosynthesis protein HemD; Function of strongly homologous gene; enzyme.	0.647
NIDE0561	hemH	NIDE0561	NIDE1216	Radical SAM superfamily protein, putative Coenzyme PQQ synthesis protein E; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.	0.975
NIDE0561	hemY	NIDE0561	NIDE1217	Radical SAM superfamily protein, putative Coenzyme PQQ synthesis protein E; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Protoporphyrinogen oxidase; Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX.	0.752
NIDE2242	NIDE0206	NIDE2242	NIDE0206	Homologs of previously reported genes of unknown function.	Protein of unknown function, CbiX domain; No homology to any previously reported sequences; 11215515, 12055304, 12686546, 12869542, 16042605, 16835730.	0.589
NIDE2242	NIDE0561	NIDE2242	NIDE0561	Homologs of previously reported genes of unknown function.	Radical SAM superfamily protein, putative Coenzyme PQQ synthesis protein E; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.941
NIDE2242	NIDE2243	NIDE2242	NIDE2243	Homologs of previously reported genes of unknown function.	Protein of unknown function; No homology to any previously reported sequences.	0.773
NIDE2242	NIDE2245	NIDE2242	NIDE2245	Homologs of previously reported genes of unknown function.	Membrane protein of unknown function, putative 4Fe-4S ferredoxin; No homology to any previously reported sequences; 2600971, 3932661.	0.539