STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE2265Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (490 aa)    
Predicted Functional Partners:
NIDE2267
Sigma-54 dependent DNA-binding response regulator; Function of strongly homologous gene; putative regulator.
   
  0.981
NIDE0858
Putative Phosphate regulon transcriptional regulatory protein phoB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
   0.972
NIDE1859
Membrane protein of unknown function, putative Response regulator with Hpt domain; No homology to any previously reported sequences; 11406410, 11489844, 11934609, 14636076, 1482126, 16176121, 18076326, 7699720.
 
 0.912
NIDE2266
Exported protein of unknown function; No homology to any previously reported sequences.
      0.907
NIDE2070
Protein of unknown function, putative Response regulator with PAS domain S-box; No homology to any previously reported sequences; 14982921, 15009198, 16176121, 18076326, 7699720, 9301332, 9382818.
 
 
   0.906
rpoN
RNA polymerase, sigma-54 (sigma N) factor; Function of homologous gene experimentally demonstrated in an other organism; factor.
     
 0.902
NIDE2217
Sigma-54 dependent transcriptional regulator; Function of strongly homologous gene; regulator.
    
  0.902
cusR
Transcriptional regulatory protein CusR; Function of strongly homologous gene; regulator.
 
   0.873
phoB
Phosphate regulon transcriptional regulator PhoB; Function of strongly homologous gene; regulator.
 
   0.860
NIDE0805
Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
0.839
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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