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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE2267Sigma-54 dependent DNA-binding response regulator; Function of strongly homologous gene; putative regulator. (471 aa)    
Predicted Functional Partners:
NIDE2265
Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
   
  0.982
rpoN
RNA polymerase, sigma-54 (sigma N) factor; Function of homologous gene experimentally demonstrated in an other organism; factor.
 
  
 0.939
NIDE2217
Sigma-54 dependent transcriptional regulator; Function of strongly homologous gene; regulator.
  
  
 
0.917
NIDE2266
Exported protein of unknown function; No homology to any previously reported sequences.
       0.818
NIDE2264
Homologs of previously reported genes of unknown function.
       0.517
NIDE2290
Two-component system, NtrC family, nitrogen regulation response regulator NtrX; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
  
0.489
NIDE2654
Chemosensory pili system protein ChpA (sensor histidine kinase/response regulator); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.470
NIDE1772
Putative Sensor histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.431
NIDE3284
Putative Histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.427
fliM
Flagellar motor switch protein FliM; Function of strongly homologous gene; structure.
  
  
 0.426
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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