STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE2283Putative Sensor histidine kinase FleS; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (429 aa)    
Predicted Functional Partners:
fleR
Sigma-54 dependent response regulator FleR; Function of strongly homologous gene; regulator.
 
 
   0.901
NIDE2070
Protein of unknown function, putative Response regulator with PAS domain S-box; No homology to any previously reported sequences; 14982921, 15009198, 16176121, 18076326, 7699720, 9301332, 9382818.
 
 
 0.849
phoB
Phosphate regulon transcriptional regulator PhoB; Function of strongly homologous gene; regulator.
 
 
   0.823
NIDE2282
Protein of unknown function, TPR-like; No homology to any previously reported sequences; 14659697, 1882418, 7667876, 9482716.
       0.820
NIDE2290
Two-component system, NtrC family, nitrogen regulation response regulator NtrX; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
 
 0.803
NIDE0858
Putative Phosphate regulon transcriptional regulatory protein phoB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
 
   0.793
NIDE1858
Putative Response regulator, CheY-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
 
   0.790
NIDE1229
Response regulator; Function of strongly homologous gene; regulator.
  
 
   0.784
NIDE2412
Signal transduction response regulator; Function of strongly homologous gene; regulator.
  
 
   0.784
NIDE3585
Putative Response regulator, CheY-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
 
   0.779
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (28%) [HD]