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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fleRSigma-54 dependent response regulator FleR; Function of strongly homologous gene; regulator. (472 aa)    
Predicted Functional Partners:
NIDE2283
Putative Sensor histidine kinase FleS; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   0.907
NIDE2282
Protein of unknown function, TPR-like; No homology to any previously reported sequences; 14659697, 1882418, 7667876, 9482716.
       0.825
tyrA
Prephenate dehydrogenase; Function of strongly homologous gene; enzyme.
      
 0.742
rpoN
RNA polymerase, sigma-54 (sigma N) factor; Function of homologous gene experimentally demonstrated in an other organism; factor.
 
   
 0.733
flgB
Flagellar basal-body rod protein FlgB; Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.
  
  
 0.696
NIDE2290
Two-component system, NtrC family, nitrogen regulation response regulator NtrX; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
  
0.628
flgC
Flagellar basal-body rod protein FlgC; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the flagella basal body rod proteins family.
  
    0.622
fliG
Flagellar motor switch protein FliG; Function of homologous gene experimentally demonstrated in an other organism; structure.
  
  
 0.598
fliE
Flagellar hook-basal body complex protein FliE; Function of homologous gene experimentally demonstrated in an other organism; structure.
  
  
 0.570
fliF
Flagellar M-ring protein FliF; The M ring may be actively involved in energy transduction. Belongs to the FliF family.
  
  
 0.545
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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