STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
csrACarbon storage regulator; A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'- UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW. (81 aa)    
Predicted Functional Partners:
fliW
Flagellar assembly factor FliW; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
 
 
 0.999
NIDE2320
Putative Second flagellar hook-filament junction protein FlgL; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.
 
  
 0.879
fliS
Flagellin-specific chaperone FliS; Function of homologous gene experimentally demonstrated in an other organism; factor.
 
  
 0.869
dksA
DnaK suppressor protein (modular protein); Function of homologous gene experimentally demonstrated in an other organism; regulator.
  
  
 0.839
fliC
Flagellin, class B; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
  
 0.829
ihfA
Integration host factor, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; factor; Belongs to the bacterial histone-like protein family.
  
 
 0.814
flgK
First flagellar hook-filament junction protein FlgK; Function of homologous gene experimentally demonstrated in an other organism; structure.
 
  
 0.808
deaD
DEAD-box RNA helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the DEAD box helicase family.
      
 0.770
cspA
Cold shock protein CspA; Function of homologous gene experimentally demonstrated in an other organism; factor.
   
  
 0.675
flgD
Flagellar hook capping protein FlgD (fragment); Function of homologous gene experimentally demonstrated in an other organism; structure.
 
    0.670
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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