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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fliSFlagellin-specific chaperone FliS; Function of homologous gene experimentally demonstrated in an other organism; factor. (130 aa)    
Predicted Functional Partners:
fliC
Flagellin, class B; Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.
 
 
 0.998
flgK
First flagellar hook-filament junction protein FlgK; Function of homologous gene experimentally demonstrated in an other organism; structure.
 
 
 0.996
NIDE2341
Putative Flagellar capping protein FliD; Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.
 
 
 0.995
flgM
Anti-sigma 28 factor FlgM; Function of homologous gene experimentally demonstrated in an other organism; regulator.
  
 
 0.992
NIDE2320
Putative Second flagellar hook-filament junction protein FlgL; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative structure.
 
 
 0.990
NIDE2290
Two-component system, NtrC family, nitrogen regulation response regulator NtrX; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
  
 0.987
flhA
Flagellar biosynthetic protein FlhA, export component; Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin; Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.
 
 
 0.983
flaG
Flagellar protein FlaG; Function of strongly homologous gene; structure.
 
  
 0.980
fliW
Flagellar assembly factor FliW; Acts as an anti-CsrA protein, binds CsrA and prevents it from repressing translation of its target genes, one of which is flagellin. Binds to flagellin and participates in the assembly of the flagellum.
 
  
 0.976
flgC
Flagellar basal-body rod protein FlgC; Function of homologous gene experimentally demonstrated in an other organism; structure; Belongs to the flagella basal body rod proteins family.
 
  
 0.962
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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