STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE2372Putative Response regulator with ATPase domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator. (299 aa)    
Predicted Functional Partners:
NIDE2371
Putative Phosphorelay protein, contains HPt domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
  
    0.827
NIDE2370
Putative Response regulator receiver modulated Serine phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
    0.816
NIDE2369
Putative Anti-sigma factor antagonist; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the anti-sigma-factor antagonist family.
  
    0.707
NIDE2368
Putative Anti-sigma factor antagonist; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor; Belongs to the anti-sigma-factor antagonist family.
 
    0.687
cheR-2
Chemotaxis protein methyltransferase CheR; Function of homologous gene experimentally demonstrated in an other organism; regulator.
 
    0.599
cheB-2
Chemotaxis methylesterase CheB; Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid. Belongs to the CheB family.
  
    0.598
cheD
Chemoreceptor glutamine deamidase CheD; Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis; Belongs to the CheD family.
 
  
 0.597
cheM
Globin-coupled methyl-accepting chemotaxis protein (modular protein); Function of strongly homologous gene; regulator.
 
 
 0.534
NIDE0805
Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.526
NIDE0815
Putative Hybrid histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.510
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.