Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
wecBUDP-N-acetylglucosamine 2-epimerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the UDP-N-acetylglucosamine 2-epimerase family. (366 aa)    
Predicted Functional Partners:
NIDE2831
UDP-glucose/GDP-mannose dehydrogenase family protein; Function of strongly homologous gene; enzyme; Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
 
 
 0.994
glmU
Bifunctional protein GlmU; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain.
    
 0.917
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily.
  
 
  0.909
galU
UTP--glucose-1-phosphate uridylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.867
manC/pmi
Bifunctional Mannose-1-phosphate guanylyltransferase/Mannose-6-phosphate isomerase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the mannose-6-phosphate isomerase type 2 family.
    
 0.860
rfbA
Glucose-1-phosphate thymidylyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.829
NIDE3821
Putative Mannose-1-phosphate guanylyltransferase (GDP); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
 0.822
lpxA
Acyl-[acyl-carrier-protein]--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
    
  0.812
NIDE3420
Putative Phospho-N-acetylmuramoyl-pentapeptide-transferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 0.806
rfbF
Glucose-1-phosphate cytidylyltransferase; Function of strongly homologous gene; enzyme.
    
  0.804
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.