STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
yefM-2Addiction module antitoxin yefM; Antitoxin component of a type II toxin-antitoxin (TA) system. (83 aa)    
Predicted Functional Partners:
yoeB
Addiction module toxin YoeB; Function of homologous gene experimentally demonstrated in an other organism; factor.
 
 
 0.994
stbE
Addiction module toxin; Function of strongly homologous gene; cell process.
   
 
 0.806
higB
Toxin of plasmid maintenance system; Function of strongly homologous gene; extrachromosomal origin.
      
 0.764
mazE
Antitoxin MazE; Function of homologous gene experimentally demonstrated in an other organism; factor.
      
 0.650
mazF
Toxin MazF; Toxic component of a type II toxin-antitoxin (TA) system.
      
 0.639
pilC
Type IV pilus biogenesis protein PilC; Function of strongly homologous gene; transporter.
      
 0.627
pilR
Transcriptional regulatory protein pilR; Function of strongly homologous gene; regulator.
      
 0.627
NIDE2003
Addiction module toxin, Txe/YoeB family; Function of strongly homologous gene; cell process.
  
 
 0.627
panC
Pantoate--beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
      
 0.621
ilvE
Branched-chain amino acid aminotransferase; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
      
 0.621
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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