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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE2415Putative Exopolyphosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (517 aa)    
Predicted Functional Partners:
ppk
Polyphosphate kinase; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family.
  
 0.944
gppA
Putative Exopolyphosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
  
 
0.926
relA
GTP pyrophosphokinase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
  
 
 0.916
phoU
Phosphate transport system protein PhoU; Plays a role in the regulation of phosphate uptake.
     
 0.820
pstA
Phosphate ABC transporter, auxiliary and permease protein (modular protein); Function of strongly homologous gene; transporter.
     
 0.786
pstB
Phosphate ABC transporter, ATP-binding protein; Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system; Belongs to the ABC transporter superfamily. Phosphate importer (TC 3.A.1.7) family.
     
 0.776
pstS
Phosphate ABC transporter, periplasmic phosphate-binding protein; Function of homologous gene experimentally demonstrated in an other organism; transporter.
     
 0.708
NIDE2419
Putative Phosphate ABC transporter, permease protein with WD40-like region (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
     
 0.701
NIDE0147
Putative Polyphosphate kinase 2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.515
NIDE3880
Conserved protein of unknown function, putative Polyphosphate kinase; Homologs of previously reported genes of unknown function; 12486232.
 
  
 0.441
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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