close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE2455Putative Ferredoxin-NADP(+) reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (456 aa)    
Predicted Functional Partners:
gltB
Glutamate synthase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.999
fdx
2Fe-2S ferredoxin; Function of strongly homologous gene; carrier.
    
 0.936
fdxB
2Fe-2S ferredoxin; Function of strongly homologous gene; carrier.
    
 0.936
NIDE0722
Putative FMN reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.867
cyp
Cytochrome P450; Function of strongly homologous gene; enzyme; Belongs to the cytochrome P450 family.
     
 0.688
NIDE0407
Putative Sulfite reductase, contains SirA-like domain (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
  
  
 0.525
pyrD
Dihydroorotate dehydrogenase; Catalyzes the conversion of dihydroorotate to orotate.
  
 
 0.524
fumC
Fumarate hydratase, class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
   
 
 0.489
gdhA
Glutamate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
  
 
 0.452
cbiX
Sirohydrochlorin cobaltochelatase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.440
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (30%) [HD]