| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| NIDE2465 | NIDE2640 | NIDE2465 | NIDE2640 | Protein of unknown function, TPR-like; No homology to any previously reported sequences; 1882418, 7667876, 9482716. | Protein of unknown function, TPR-like; No homology to any previously reported sequences; 15189147, 1882418, 7667876, 7748903, 8690703, 9482716. | 0.534 |
| NIDE2465 | accB | NIDE2465 | NIDE2468 | Protein of unknown function, TPR-like; No homology to any previously reported sequences; 1882418, 7667876, 9482716. | Acetyl CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 0.509 |
| NIDE2465 | aroQ | NIDE2465 | NIDE2466 | Protein of unknown function, TPR-like; No homology to any previously reported sequences; 1882418, 7667876, 9482716. | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.588 |
| NIDE2465 | coaBC | NIDE2465 | NIDE2464 | Protein of unknown function, TPR-like; No homology to any previously reported sequences; 1882418, 7667876, 9482716. | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.827 |
| NIDE2465 | efp | NIDE2465 | NIDE2467 | Protein of unknown function, TPR-like; No homology to any previously reported sequences; 1882418, 7667876, 9482716. | Elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.509 |
| NIDE2465 | gmk | NIDE2465 | NIDE2462 | Protein of unknown function, TPR-like; No homology to any previously reported sequences; 1882418, 7667876, 9482716. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.821 |
| NIDE2465 | hflX | NIDE2465 | NIDE2459 | Protein of unknown function, TPR-like; No homology to any previously reported sequences; 1882418, 7667876, 9482716. | Putative GTPase HflX, GTP-binding protein; GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family. | 0.590 |
| NIDE2465 | nth | NIDE2465 | NIDE2460 | Protein of unknown function, TPR-like; No homology to any previously reported sequences; 1882418, 7667876, 9482716. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.648 |
| NIDE2465 | rpoZ | NIDE2465 | NIDE2463 | Protein of unknown function, TPR-like; No homology to any previously reported sequences; 1882418, 7667876, 9482716. | DNA-directed RNA polymerase, omega subunit (modular protein); Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.819 |
| NIDE2465 | yicC | NIDE2465 | NIDE2461 | Protein of unknown function, TPR-like; No homology to any previously reported sequences; 1882418, 7667876, 9482716. | Homologs of previously reported genes of unknown function. | 0.648 |
| NIDE2640 | NIDE2465 | NIDE2640 | NIDE2465 | Protein of unknown function, TPR-like; No homology to any previously reported sequences; 15189147, 1882418, 7667876, 7748903, 8690703, 9482716. | Protein of unknown function, TPR-like; No homology to any previously reported sequences; 1882418, 7667876, 9482716. | 0.534 |
| accB | NIDE2465 | NIDE2468 | NIDE2465 | Acetyl CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Protein of unknown function, TPR-like; No homology to any previously reported sequences; 1882418, 7667876, 9482716. | 0.509 |
| accB | aroQ | NIDE2468 | NIDE2466 | Acetyl CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | 0.812 |
| accB | coaBC | NIDE2468 | NIDE2464 | Acetyl CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Coenzyme A biosynthesis bifunctional protein CoaBC; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.539 |
| accB | efp | NIDE2468 | NIDE2467 | Acetyl CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Elongation factor P (EF-P); Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.849 |
| accB | gmk | NIDE2468 | NIDE2462 | Acetyl CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Guanylate kinase; Essential for recycling GMP and indirectly, cGMP. | 0.525 |
| accB | nth | NIDE2468 | NIDE2460 | Acetyl CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.469 |
| accB | rpoZ | NIDE2468 | NIDE2463 | Acetyl CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | DNA-directed RNA polymerase, omega subunit (modular protein); Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.541 |
| accB | yicC | NIDE2468 | NIDE2461 | Acetyl CoA carboxylase, biotin carboxyl carrier protein; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA. | Homologs of previously reported genes of unknown function. | 0.446 |
| aroQ | NIDE2465 | NIDE2466 | NIDE2465 | 3-dehydroquinate dehydratase, type II; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. | Protein of unknown function, TPR-like; No homology to any previously reported sequences; 1882418, 7667876, 9482716. | 0.588 |