STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
radCDNA repair protein RadC homolog; Function of strongly homologous gene; factor; Belongs to the UPF0758 family. (220 aa)    
Predicted Functional Partners:
recN
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
  
   
 0.800
maf
Septum formation protein Maf-like; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
  
 0.795
NIDE2506
Putative Type I restriction-modification system, site-specific deoxyribonuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.782
NIDE2502
Putative Type I restriction-modification system, N-6 adenine-specific DNA methylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.781
radA
DNA recombination protein RadA; DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.
     
 0.778
NIDE2503
Putative Type I restriction-modification system, specificity protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
       0.773
NIDE2504
Homologs of previously reported genes of unknown function.
       0.773
NIDE2505
Putative Transcriptional regulator (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
       0.773
NIDE1014
Putative Cell shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
  
 0.771
recQ
ATP-dependent DNA helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.771
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.