close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
radCDNA repair protein RadC homolog; Function of strongly homologous gene; factor; Belongs to the UPF0758 family. (220 aa)    
Predicted Functional Partners:
NIDE2506
Putative Type I restriction-modification system, site-specific deoxyribonuclease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.786
NIDE2502
Putative Type I restriction-modification system, N-6 adenine-specific DNA methylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.779
NIDE2503
Putative Type I restriction-modification system, specificity protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative factor.
       0.773
NIDE2504
Homologs of previously reported genes of unknown function.
       0.773
NIDE2505
Putative Transcriptional regulator (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
       0.773
maf
Septum formation protein Maf-like; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
  
 0.771
NIDE1014
Putative Cell shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
  
 0.758
NIDE1089
Putative Phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
    0.744
NIDE2734
Putative Competence protein ComEC/Rec2 related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.558
cinA
CinA-like protein; Function of strongly homologous gene; cell process; Belongs to the CinA family.
     
 0.485
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (22%) [HD]