Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
rtcBHomologs of previously reported genes of unknown function; 9738023; Belongs to the RtcB family. (483 aa)    
Predicted Functional Partners:
NIDE2518
Homologs of previously reported genes of unknown function.
 
 0.993
NIDE2520
Homologs of previously reported genes of unknown function.
       0.671
NIDE2521
Exported protein of unknown function; No homology to any previously reported sequences.
       0.618
sdhB
Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
    0.555
rhlE
ATP-dependent RNA helicase; Function of strongly homologous gene; enzyme; Belongs to the DEAD box helicase family.
   
 0.517
rhlE-2
ATP-dependent RNA helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 0.517
deaD
DEAD-box RNA helicase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the DEAD box helicase family.
   
 0.517
NIDE3078
Putative 2'-5' RNA ligase; Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester; Belongs to the 2H phosphoesterase superfamily. ThpR family.
 
   
 0.492
pepP
Xaa-Pro aminopeptidase; Function of strongly homologous gene; enzyme; Belongs to the peptidase M24B family.
       0.427
NIDE2515
Exported protein of unknown function; No homology to any previously reported sequences; 8866482.
 
     0.415
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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