Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
radC2DNA repair protein RadC homolog; Function of strongly homologous gene; cell process; Belongs to the UPF0758 family. (238 aa)    
Predicted Functional Partners:
maf
Septum formation protein Maf-like; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
  
  
 0.795
NIDE1014
Putative Cell shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
  
 0.771
NIDE1089
Putative Phosphoribosyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
    0.635
NIDE2734
Putative Competence protein ComEC/Rec2 related protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
  
 0.633
fusA-2
Elongation factor G (EF-G); Function of homologous gene experimentally demonstrated in an other organism; factor.
  
    0.591
NIDE2564
Protein of unknown function; No homology to any previously reported sequences.
       0.530
mutL
DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.
 
   
 0.514
smf
Protein SMF, putative DNA protecting protein DprA; Function of strongly homologous gene; phenotype.
  
  
 0.500
mutS
DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.
 
   
 0.477
cinA
CinA-like protein; Function of strongly homologous gene; cell process; Belongs to the CinA family.
     
 0.475
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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