| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| accA | dnaE2 | NIDE2583 | NIDE2582 | Acetyl-CoA carboxylase, carboxytransferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | DNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.841 |
| dnaE2 | accA | NIDE2582 | NIDE2583 | DNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Acetyl-CoA carboxylase, carboxytransferase, alpha subunit; Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA. | 0.841 |
| dnaE2 | dnaN | NIDE2582 | NIDE0002 | DNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.988 |
| dnaE2 | dnaX | NIDE2582 | NIDE0278 | DNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.984 |
| dnaE2 | holA | NIDE2582 | NIDE4236 | DNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative DNA polymerase III, delta subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.986 |
| dnaE2 | holB | NIDE2582 | NIDE2926 | DNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | DNA polymerase III, delta' subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.986 |
| dnaE2 | mutM | NIDE2582 | NIDE0833 | DNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | DNA-formamidopyrimidine glycosylase and DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.795 |
| dnaE2 | mutT | NIDE2582 | NIDE1915 | DNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Mutator MutT protein; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.771 |
| dnaE2 | mutY | NIDE2582 | NIDE1914 | DNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | A/G-specific adenine glycosylase (fragment); Function of strongly homologous gene; enzyme. | 0.742 |
| dnaE2 | recA | NIDE2582 | NIDE1705 | DNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.792 |
| dnaE2 | ssb | NIDE2582 | NIDE0790 | DNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Single-stranded DNA-binding protein; Function of homologous gene experimentally demonstrated in an other organism; cell process. | 0.883 |
| dnaN | dnaE2 | NIDE0002 | NIDE2582 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.988 |
| dnaN | dnaX | NIDE0002 | NIDE0278 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | 0.988 |
| dnaN | holA | NIDE0002 | NIDE4236 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Putative DNA polymerase III, delta subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.991 |
| dnaN | holB | NIDE0002 | NIDE2926 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III, delta' subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.988 |
| dnaN | mutY | NIDE0002 | NIDE1914 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | A/G-specific adenine glycosylase (fragment); Function of strongly homologous gene; enzyme. | 0.843 |
| dnaN | recA | NIDE0002 | NIDE1705 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.922 |
| dnaN | ssb | NIDE0002 | NIDE0790 | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Single-stranded DNA-binding protein; Function of homologous gene experimentally demonstrated in an other organism; cell process. | 0.543 |
| dnaX | dnaE2 | NIDE0278 | NIDE2582 | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | DNA polymerase III, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.984 |
| dnaX | dnaN | NIDE0278 | NIDE0002 | DNA polymerase III, gamma and tau subunits; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. | DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.988 |
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