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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE2619Conserved protein of unknown function, putative dual specificity protein phosphatase; Homologs of previously reported genes of unknown function; 12678841, 9818190. (164 aa)    
Predicted Functional Partners:
NIDE2618
Protein of unknown function; No homology to any previously reported sequences.
       0.773
NIDE1523
Protein of unknown function; No homology to any previously reported sequences; 14731533, 15335710, 1639195, 7531822, 7953536.
   
 0.759
NIDE3282
Exported protein of unknown function, contains WD40 repeats; No homology to any previously reported sequences; 1909108.
   
 0.759
NIDE2620
Putative Type I restriction-modification system, restriction subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.697
lepA
GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
    
  0.667
NIDE1905
Homologs of previously reported genes of unknown function.
  
     0.517
NIDE3861
Homologs of previously reported genes of unknown function.
   
 
 0.474
NIDE0308
Protein of unknown function, contains Ankyrin and Tetratricopeptide repeats; No homology to any previously reported sequences; 14659697, 7667876, 8108379, 9482716.
   
 0.463
yahD
Conserved protein of unknown function, contains Ankyrin repeats; Homologs of previously reported genes of unknown function; 15063798, 8108379.
   
 0.460
NIDE3602
Exported protein of unknown function, contains Ankyrin repeats; No homology to any previously reported sequences; 8108379.
   
 0.460
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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