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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE2622Protein of unknown function; No homology to any previously reported sequences. (48 aa)    
Predicted Functional Partners:
hsdM2
Type I restriction-modification system, methyltransferase subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 
 0.973
NIDE2624
Putative Type I restriction-modification system, specificity subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.964
hsdM
Type I restriction endonuclease, M subunit (modular protein); Function of strongly homologous gene; enzyme.
 
 
 0.862
NIDE2623
Conserved protein of unknown function, RhuM family; Homologs of previously reported genes of unknown function; 9922266.
       0.787
NIDE0136
Putative Type I restriction endonuclease, R subunit; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
     0.730
NIDE1898
Putative Type I restriction system, N-6 adenine-specific DNA methylase HsdM; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.489
NIDE2146
Protein of unknown function; No homology to any previously reported sequences.
  
 
 0.489
NIDE2502
Putative Type I restriction-modification system, N-6 adenine-specific DNA methylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.489
NIDE3670
DNA modification methylase; Function of strongly homologous gene; enzyme.
  
 
 0.489
NIDE2626
Putative HTH-type transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
    0.470
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.