close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE2630Protein of unknown function, putative Protease with integrin domain; No homology to any previously reported sequences; 11517925, 7845208, 8439290. (653 aa)    
Predicted Functional Partners:
NIDE0522
Putative Ribonuclease Z; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
   0.822
NIDE1576
Putative cAMP phosphodiesterase, class-II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
   0.822
NIDE3200
Putative Ribonuclease Z; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
   0.822
nuoF
NADH-quinone oxidoreductase, subunit F; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Belongs to the complex I 51 kDa subunit family.
   
    0.644
fdsB
Formate dehydrogenase, beta subunit; Function of strongly homologous gene; enzyme.
   
    0.644
nuoF-2
NADH-quinone oxidoreductase, subunit F; Function of homologous gene experimentally demonstrated in an other organism; carrier.
   
    0.644
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
   
 
 0.528
NIDE2224
Putative ATPase, AAA family; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
     0.481
NIDE3638
Protein of unknown function, putative ATPase; No homology to any previously reported sequences.
  
     0.432
nuoCD
NADH-quinone oxidoreductase, subunits C and D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
   0.428
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.