Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE2638FAD/FMN-containing dehydrogenase, putative glycolate oxidase, fused subunits GlcD and GlcF; Function of strongly homologous gene; enzyme. (946 aa)    
Predicted Functional Partners:
NIDE2637
Conserved exported protein of unknown function, putative Cytochrome c; Homologs of previously reported genes of unknown function.
       0.788
ghrB
Glyoxylate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
 
 0.760
nuoCD
NADH-quinone oxidoreductase, subunits C and D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
  
   0.679
NIDE3330
Conserved protein of unknown function, SDR family; Homologs of previously reported genes of unknown function; 7742302.
  
 
 0.658
sdhB
Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
   
 
 0.656
gapA
Glyceraldehyde-3-phosphate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
  
 
 0.642
NIDE1136
Conserved exported protein of unknown function, DUF336; Homologs of previously reported genes of unknown function.
  
  
 0.592
NIDE2636
Protein of unknown function, moaD-like; No homology to any previously reported sequences.
       0.590
sdhE
Succinate dehydrogenase, subunit C; Function of strongly homologous gene; enzyme.
   
 
 0.564
gltB
Glutamate synthase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
     
 0.548
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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