Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ghrBGlyoxylate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (323 aa)    
Predicted Functional Partners:
ttuD
Putative Hydroxypyruvate reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 0.963
NIDE1160
Aminotransferase, class V; Function of strongly homologous gene; enzyme.
  
 
 0.918
NIDE4284
Putative Phosphoglycolate phosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
    
  0.907
NIDE2638
FAD/FMN-containing dehydrogenase, putative glycolate oxidase, fused subunits GlcD and GlcF; Function of strongly homologous gene; enzyme.
   
 
 0.760
pgm
Phosphoglucomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
   0.622
NIDE2637
Conserved exported protein of unknown function, putative Cytochrome c; Homologs of previously reported genes of unknown function.
       0.542
aclA
ATP citrate lyase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.535
neuA
N-acylneuraminate cytidylyltransferase; Function of strongly homologous gene; enzyme.
      0.510
metH
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.489
NIDE1587
Protein of unknown function, putative Sensory histidine kinase with methyltransferase region; No homology to any previously reported sequences; 11369279, 11489844, 15009198, 16176121, 16622408, 18076326, 7699720, 9301332, 9382818.
     
 0.481
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.