node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
NIDE2660 | NIDE2667 | NIDE2660 | NIDE2667 | Putative Adenosylcobinamide amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative Cob(II)yrinic acid a,c-diamide reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.759 |
NIDE2660 | btuR | NIDE2660 | NIDE2669 | Putative Adenosylcobinamide amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.973 |
NIDE2660 | cbiA | NIDE2660 | NIDE2670 | Putative Adenosylcobinamide amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.788 |
NIDE2660 | cbiB | NIDE2660 | NIDE2662 | Putative Adenosylcobinamide amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Cobalamin biosynthesis protein CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.988 |
NIDE2660 | cobD | NIDE2660 | NIDE2661 | Putative Adenosylcobinamide amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Threonine-phosphate decarboxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.842 |
NIDE2660 | cobO | NIDE2660 | NIDE2666 | Putative Adenosylcobinamide amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Function of strongly homologous gene; enzyme; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.980 |
NIDE2660 | cobQ | NIDE2660 | NIDE2659 | Putative Adenosylcobinamide amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.983 |
NIDE2660 | cobS | NIDE2660 | NIDE2663 | Putative Adenosylcobinamide amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.858 |
NIDE2660 | cobT | NIDE2660 | NIDE2664 | Putative Adenosylcobinamide amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.856 |
NIDE2660 | cobU | NIDE2660 | NIDE2665 | Putative Adenosylcobinamide amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Bifunctional adenosylcobalamin biosynthesis protein CobU; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.977 |
NIDE2667 | NIDE2660 | NIDE2667 | NIDE2660 | Putative Cob(II)yrinic acid a,c-diamide reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Putative Adenosylcobinamide amidohydrolase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | 0.759 |
NIDE2667 | btuR | NIDE2667 | NIDE2669 | Putative Cob(II)yrinic acid a,c-diamide reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.819 |
NIDE2667 | cbiA | NIDE2667 | NIDE2670 | Putative Cob(II)yrinic acid a,c-diamide reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family. | 0.816 |
NIDE2667 | cbiB | NIDE2667 | NIDE2662 | Putative Cob(II)yrinic acid a,c-diamide reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Cobalamin biosynthesis protein CbiB; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group. | 0.790 |
NIDE2667 | cobD | NIDE2667 | NIDE2661 | Putative Cob(II)yrinic acid a,c-diamide reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Threonine-phosphate decarboxylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.784 |
NIDE2667 | cobO | NIDE2667 | NIDE2666 | Putative Cob(II)yrinic acid a,c-diamide reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Cob(I)yrinic acid a,c-diamide adenosyltransferase; Function of strongly homologous gene; enzyme; Belongs to the Cob(I)alamin adenosyltransferase family. | 0.817 |
NIDE2667 | cobQ | NIDE2667 | NIDE2659 | Putative Cob(II)yrinic acid a,c-diamide reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily. | 0.832 |
NIDE2667 | cobS | NIDE2667 | NIDE2663 | Putative Cob(II)yrinic acid a,c-diamide reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family. | 0.788 |
NIDE2667 | cobT | NIDE2667 | NIDE2664 | Putative Cob(II)yrinic acid a,c-diamide reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). | 0.995 |
NIDE2667 | cobU | NIDE2667 | NIDE2665 | Putative Cob(II)yrinic acid a,c-diamide reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. | Bifunctional adenosylcobalamin biosynthesis protein CobU; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.931 |