close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE2671Putative Vitamin B12 transporter BtuB precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (660 aa)    
Predicted Functional Partners:
NIDE0628
Putative TonB protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
 
 
 0.880
NIDE1031
Putative Protein TonB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
 
 
 0.876
NIDE2189
Putative Protein TonB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
 
 
 0.859
NIDE2166
Putative Protein TonB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
 
 
 0.852
parA
Chromosomal partitioning ATPase ParA; Function of strongly homologous gene; enzyme.
    
 
 0.833
NIDE0467
Exported protein of unknown function, containing C-terminal TonB domain; No homology to any previously reported sequences.
   
 
 0.828
NIDE3361
Putative Protein TolA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
   
 
 0.828
btuR
Cob(I)yrinic acid a,c-diamide adenosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.779
cbiA
Cobyrinic acid a,c-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
     
 0.769
cobU
Bifunctional adenosylcobalamin biosynthesis protein CobU; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.764
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.