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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE2674Putative Vitamin B12 import system, periplasmic binding protein BtuF; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (340 aa)    
Predicted Functional Partners:
btuC
Vitamin B12 import system, permease protein BtuC; Function of strongly homologous gene; transporter; Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.
 
 
 0.998
NIDE2672
Putative Vitamin B12 import system, ATP-binding protein BtuD; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.997
NIDE2061
Conserved protein of unknown function, contains FMN-binding split barrel; Homologs of previously reported genes of unknown function; 12686112.
 
    0.633
NIDE2675
Protein of unknown function; No homology to any previously reported sequences.
       0.613
NIDE2671
Putative Vitamin B12 transporter BtuB precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
  
 0.603
NIDE2676
Homologs of previously reported genes of unknown function.
       0.596
cobS
Cobalamin synthase; Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'- phosphate; Belongs to the CobS family.
 
   
 0.579
NIDE4379
Conserved protein of unknown function, contains FMN-binding split barrel; Homologs of previously reported genes of unknown function; 11786019, 12686112, 15858270.
  
    0.570
cobU
Bifunctional adenosylcobalamin biosynthesis protein CobU; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
     0.552
cobT
Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase; Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB).
 
   
 0.530
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.