STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE2691Putative D-alanine-poly(phosphoribitol) ligase, subunit 2 (modular protein); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme. (90 aa)    
Predicted Functional Partners:
nuoCD
NADH-quinone oxidoreductase, subunits C and D; Function of homologous gene experimentally demonstrated in an other organism; enzyme; In the N-terminal section; belongs to the complex I 30 kDa subunit family.
   
 0.985
rplU
50S ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family.
   
  0.843
rplJL
Fused 50S ribosomal proteins L10 and L7/L12 (modular protein); Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family.
   
 0.824
NIDE2692
Putative D-alanine-poly(phosphoribitol) ligase, subunit 1; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the ATP-dependent AMP-binding enzyme family.
  
   0.824
NIDE1742
Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.784
rplQ
50S ribosomal protein L17; Function of homologous gene experimentally demonstrated in an other organism; structure.
   
  0.782
fabD
Malonyl-CoA-(acyl-carrier-protein) transacylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.777
rplM
50S ribosomal protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.
   
  0.773
rplT
50S ribosomal protein L20; Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.
   
  0.760
NIDE1587
Protein of unknown function, putative Sensory histidine kinase with methyltransferase region; No homology to any previously reported sequences; 11369279, 11489844, 15009198, 16176121, 16622408, 18076326, 7699720, 9301332, 9382818.
  
 
 0.759
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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