Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NIDE2692Putative D-alanine-poly(phosphoribitol) ligase, subunit 1; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the ATP-dependent AMP-binding enzyme family. (521 aa)    
Predicted Functional Partners:
NIDE2152
Putative Polyketide synthase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 0.995
NIDE2151
Putative Non-ribosomal peptide synthetase (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
     0.976
NIDE2157
Thioesterase, type II; Function of strongly homologous gene; enzyme.
  
 0.948
NIDE2158
Putative Regulatory protein, SyrP-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
 0.925
fabD
Malonyl-CoA-(acyl-carrier-protein) transacylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.910
fabG3
3-oxoacyl-(acyl-carrier-protein) reductase; Function of strongly homologous gene; enzyme; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
 
  
 0.907
hemL
Glutamate-1-semialdehyde-2,1-aminomutase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
  
 0.906
fabF3
3-oxoacyl-(acyl-carrier-protein) synthase; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
  
 0.904
fabF2
3-oxoacyl-(acyl-carrier-protein) synthase II; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
  
 0.903
fabF
Beta-ketoacyl ACP synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.
 
  
 0.896
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (36%) [HD]