NIDE2720 protein (Nitrospira defluvii) - STRING interaction network

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[Homology]

Score

NIDE2720

Protein of unknown function; No homology to any previously reported sequences; 16894158. (669 aa)

Predicted Functional Partners:

secY

0.817

NIDE2037

0.800

secA-2

0.646

NIDE2719

0.637

NIDE2721

0.590

ftsK

0.538

NIDE2723

0.472

NIDE2724

0.464

ribD

0.438

NIDE1742

0.437

Your Current Organism:

Nitrospira defluvii

NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NIDE1742	NIDE2720	NIDE1742	NIDE2720	Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Protein of unknown function; No homology to any previously reported sequences; 16894158.	0.437
NIDE1742	secA-2	NIDE1742	NIDE2722	Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Protein translocase, subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.	0.868
NIDE2037	NIDE2720	NIDE2037	NIDE2720	Homologs of previously reported genes of unknown function.	Protein of unknown function; No homology to any previously reported sequences; 16894158.	0.800
NIDE2037	secY	NIDE2037	NIDE1331	Homologs of previously reported genes of unknown function.	Preprotein translocase, membrane subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.	0.800
NIDE2719	NIDE2720	NIDE2719	NIDE2720	Putative Secretion protein HlyD family precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Protein of unknown function; No homology to any previously reported sequences; 16894158.	0.637
NIDE2719	NIDE2721	NIDE2719	NIDE2721	Putative Secretion protein HlyD family precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Putative Secretion protein HlyD family precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.	0.525
NIDE2719	NIDE2723	NIDE2719	NIDE2723	Putative Secretion protein HlyD family precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Peptidase, M50 family; Function of strongly homologous gene; enzyme.	0.838
NIDE2719	NIDE2724	NIDE2719	NIDE2724	Putative Secretion protein HlyD family precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Conserved protein of unknown function, contains GAF domain; Homologs of previously reported genes of unknown function; 12271124, 15708973, 9433123.	0.840
NIDE2719	secA-2	NIDE2719	NIDE2722	Putative Secretion protein HlyD family precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	Protein translocase, subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.	0.492
NIDE2720	NIDE1742	NIDE2720	NIDE1742	Protein of unknown function; No homology to any previously reported sequences; 16894158.	Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.437
NIDE2720	NIDE2037	NIDE2720	NIDE2037	Protein of unknown function; No homology to any previously reported sequences; 16894158.	Homologs of previously reported genes of unknown function.	0.800
NIDE2720	NIDE2719	NIDE2720	NIDE2719	Protein of unknown function; No homology to any previously reported sequences; 16894158.	Putative Secretion protein HlyD family precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.637
NIDE2720	NIDE2721	NIDE2720	NIDE2721	Protein of unknown function; No homology to any previously reported sequences; 16894158.	Putative Secretion protein HlyD family precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.	0.590
NIDE2720	NIDE2723	NIDE2720	NIDE2723	Protein of unknown function; No homology to any previously reported sequences; 16894158.	Peptidase, M50 family; Function of strongly homologous gene; enzyme.	0.472
NIDE2720	NIDE2724	NIDE2720	NIDE2724	Protein of unknown function; No homology to any previously reported sequences; 16894158.	Conserved protein of unknown function, contains GAF domain; Homologs of previously reported genes of unknown function; 12271124, 15708973, 9433123.	0.464
NIDE2720	ftsK	NIDE2720	NIDE0539	Protein of unknown function; No homology to any previously reported sequences; 16894158.	DNA translocase FtsK; Function of strongly homologous gene; enzyme.	0.538
NIDE2720	ribD	NIDE2720	NIDE1635	Protein of unknown function; No homology to any previously reported sequences; 16894158.	Diaminohydroxyphosphoribosylaminopyrimidine deaminase; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.	0.438
NIDE2720	secA-2	NIDE2720	NIDE2722	Protein of unknown function; No homology to any previously reported sequences; 16894158.	Protein translocase, subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.	0.646
NIDE2720	secY	NIDE2720	NIDE1331	Protein of unknown function; No homology to any previously reported sequences; 16894158.	Preprotein translocase, membrane subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.	0.817
NIDE2721	NIDE2719	NIDE2721	NIDE2719	Putative Secretion protein HlyD family precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.	Putative Secretion protein HlyD family precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.	0.525