STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE2723Peptidase, M50 family; Function of strongly homologous gene; enzyme. (715 aa)    
Predicted Functional Partners:
NIDE2724
Conserved protein of unknown function, contains GAF domain; Homologs of previously reported genes of unknown function; 12271124, 15708973, 9433123.
 
     0.943
NIDE2721
Putative Secretion protein HlyD family precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
    0.898
NIDE2719
Putative Secretion protein HlyD family precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
     0.838
secA-2
Protein translocase, subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
     0.733
NIDE3139
Putative Outer membrane efflux protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
   0.733
NIDE2718
Putative Outer membrane efflux protein precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
   0.576
NIDE3135
Conserved protein of unknown function, putative Adhesin; Homologs of previously reported genes of unknown function; 2197976, 2539596, 7519681.
  
     0.567
NIDE1185
Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
 
 
 0.513
NIDE0214
Putative large exoprotein involved in heme utilization or adhesion; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.
  
     0.491
hlyB
Type I secretion system ATPase HlyB; Function of strongly homologous gene; transporter.
 
 
 0.486
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.