Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
NIDE2724Conserved protein of unknown function, contains GAF domain; Homologs of previously reported genes of unknown function; 12271124, 15708973, 9433123. (488 aa)    
Predicted Functional Partners:
NIDE2723
Peptidase, M50 family; Function of strongly homologous gene; enzyme.
 
     0.942
NIDE2721
Putative Secretion protein HlyD family precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
 
     0.897
NIDE2719
Putative Secretion protein HlyD family precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter; Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.
 
     0.840
secA-2
Protein translocase, subunit SecA; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane.
 
     0.698
NIDE3136
Conserved protein of unknown function, putative Peptidase M50; Homologs of previously reported genes of unknown function.
  
     0.665
NIDE2718
Putative Outer membrane efflux protein precursor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
   0.504
hlyB
Type I secretion system ATPase HlyB; Function of strongly homologous gene; transporter.
 
 
 0.489
macC
ABC transporter, permease component, putative Macrolide export permease protein; Function of strongly homologous gene; transporter.
  
  
 0.477
NIDE3944
Putative ABC-type transport system, permease component; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter.
  
  
 0.477
NIDE2720
Protein of unknown function; No homology to any previously reported sequences; 16894158.
     
 0.447
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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