mtnA protein (Nitrospira defluvii) - STRING interaction network

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mtnA

5-methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P). (343 aa)

Predicted Functional Partners:

mtnP

0.963

apt

0.863

metH

0.808

rpe

0.725

NIDE0966

0.682

rlp

0.656

pheS

0.621

metF

0.523

ribH

0.512

NIDE2732

0.511

Your Current Organism:

Nitrospira defluvii

NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
NIDE0966	apt	NIDE0966	NIDE1247	Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.415
NIDE0966	metH	NIDE0966	NIDE1868	Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.636
NIDE0966	mtnA	NIDE0966	NIDE2731	Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	5-methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).	0.682
NIDE0966	rlp	NIDE0966	NIDE1881	Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	Ribulose bisphosphate carboxylase-like protein (RuBisCO type IV-like protein); Function of strongly homologous gene; enzyme.	0.669
NIDE2732	mtnA	NIDE2732	NIDE2731	Putative UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DegT/DnrJ/EryC1 family.	5-methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).	0.511
apt	NIDE0966	NIDE1247	NIDE0966	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.415
apt	mtnA	NIDE1247	NIDE2731	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	5-methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).	0.863
apt	mtnP	NIDE1247	NIDE3354	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	Putative S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.	0.939
metF	metH	NIDE0811	NIDE1868	5,10-methylenetetrahydrofolate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the methylenetetrahydrofolate reductase family.	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.998
metF	mtnA	NIDE0811	NIDE2731	5,10-methylenetetrahydrofolate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the methylenetetrahydrofolate reductase family.	5-methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).	0.523
metF	rlp	NIDE0811	NIDE1881	5,10-methylenetetrahydrofolate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the methylenetetrahydrofolate reductase family.	Ribulose bisphosphate carboxylase-like protein (RuBisCO type IV-like protein); Function of strongly homologous gene; enzyme.	0.451
metH	NIDE0966	NIDE1868	NIDE0966	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.636
metH	metF	NIDE1868	NIDE0811	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	5,10-methylenetetrahydrofolate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the methylenetetrahydrofolate reductase family.	0.998
metH	mtnA	NIDE1868	NIDE2731	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	5-methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).	0.808
metH	rlp	NIDE1868	NIDE1881	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	Ribulose bisphosphate carboxylase-like protein (RuBisCO type IV-like protein); Function of strongly homologous gene; enzyme.	0.624
mtnA	NIDE0966	NIDE2731	NIDE0966	5-methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).	Putative Aldolase, class II; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.	0.682
mtnA	NIDE2732	NIDE2731	NIDE2732	5-methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).	Putative UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme; Belongs to the DegT/DnrJ/EryC1 family.	0.511
mtnA	apt	NIDE2731	NIDE1247	5-methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).	Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.	0.863
mtnA	metF	NIDE2731	NIDE0811	5-methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).	5,10-methylenetetrahydrofolate reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the methylenetetrahydrofolate reductase family.	0.523
mtnA	metH	NIDE2731	NIDE1868	5-methylthioribose-1-phosphate isomerase; Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).	Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.	0.808

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