STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE2746Putative Cytochrome c biogenesis protein CcsA; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative transporter. (268 aa)    
Predicted Functional Partners:
hemA
Glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
     0.890
NIDE0847
Putative Cytochrome c biogenesis protein, ResB-like; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
     0.773
hemD
Porphyrin biosynthesis protein HemD; Function of strongly homologous gene; enzyme.
       0.646
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
       0.646
NIDE2747
Putative Methyltransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
       0.638
NIDE2742
Conserved protein of unknown function, contains CBS domain pair; Homologs of previously reported genes of unknown function; 15326606, 9020585.
       0.554
hemB
Delta-aminolevulinic acid dehydratase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the ALAD family.
       0.548
ribF
Riboflavin biosynthesis protein RibF; Function of strongly homologous gene; enzyme; Belongs to the ribF family.
       0.547
tilS
tRNA(Ile)-lysidine synthase; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
       0.451
hpt
Hypoxanthine phosphoribosyltransferase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
       0.450
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.