Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
NIDE2772Ferredoxin, 2Fe-2S; Function of strongly homologous gene; carrier. (108 aa)    
Predicted Functional Partners:
nuoE
NADH-quinone oxidoreductase, subunit E; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.759
fdsG
Formate dehydrogenase, gamma subunit; Function of strongly homologous gene; enzyme.
  
 
 0.759
NIDE2455
Putative Ferredoxin-NADP(+) reductase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
 
 0.745
gltD
Glutamate synthase, beta subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.745
NIDE0232
Putative NADH-quinone oxidoreductase, subunit G; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.664
nuoG
NADH-quinone oxidoreductase, subunit G; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. Belongs to the complex I 75 kDa subunit family.
  
 
 0.664
fdsA
Formate dehydrogenase, alpha subunit; Function of strongly homologous gene; enzyme.
  
 
 0.664
aoxB
Arsenite oxidase, large subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
  
 
 0.664
NIDE2770
Homologs of previously reported genes of unknown function.
       0.644
moaB
Molybdenum cofactor biosynthesis protein B; May be involved in the biosynthesis of molybdopterin. Belongs to the MoaB/Mog family.
       0.618
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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