Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NIDE2795Transcriptional regulator, AraC family; Function of strongly homologous gene; regulator. (341 aa)    
Predicted Functional Partners:
NIDE2190
Putative HTH-type transcriptional regulator, AraC family (fragment); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
  
     0.762
rpoA
DNA-directed RNA polymerase, alpha subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
  
 
 
 0.724
NIDE2794
Methyltransferase, ubiE family; Function of strongly homologous gene; enzyme.
 
     0.667
NIDE2126
DNA-binding transcriptional regulator, tetR-type; Function of strongly homologous gene; factor.
  
   
 0.548
NIDE2793
Conserved protein of unknown function, putative Alkylhydroperoxidase AhpD; Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity. Belongs to the AhpD family.
     
 0.481
NIDE3333
Putative HTH-type transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative regulator.
 
 
 0.480
NIDE0963
Protein of unknown function, contains acyl transferase and methyltransferase regions; No homology to any previously reported sequences; 2071574, 7893120.
  
   
 0.465
NIDE1435
Conserved exported protein of unknown function, DUF302; Homologs of previously reported genes of unknown function.
  
     0.418
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
Server load: low (12%) [HD]