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The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NIDE2803Transcriptional regulator, LysR family; Function of strongly homologous gene; regulator; Belongs to the LysR transcriptional regulatory family. (300 aa)    
Predicted Functional Partners:
NIDE2805
Major facilitator superfamily transporter, putative tetracycline resistance protein; Function of strongly homologous gene; transporter.
 
  
 0.820
gltB
Glutamate synthase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.537
tpm
Thiopurine S-methyltransferase; Function of strongly homologous gene; enzyme.
       0.513
NIDE3617
Homologs of previously reported genes of unknown function.
  
     0.512
NIDE2806
Protein of unknown function; No homology to any previously reported sequences.
       0.510
NIDE2126
DNA-binding transcriptional regulator, tetR-type; Function of strongly homologous gene; factor.
  
 
 
 0.457
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.