Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
glpEThiosulfate sulfurtransferase GlpE (modular protein); Function of homologous gene experimentally demonstrated in an other organism; enzyme. (147 aa)    
Predicted Functional Partners:
NIDE3220
Putative 3-mercaptopyruvate sulfurtransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
  
 
 0.826
cysK
Cysteine synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
  
 0.786
nirA
Ferredoxin-nitrite reductase; Function of strongly homologous gene; enzyme; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
    
 
 0.754
NIDE1742
Putative Multi-domain non-ribosomal peptide synthetase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
   
   0.743
gltB
Glutamate synthase, alpha subunit; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.702
nirK
Copper-containing nitrite reductase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
      
 0.627
cysC
Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate.
      
 0.478
NIDE2813
Conserved protein of unknown function, DCC family; Homologs of previously reported genes of unknown function.
       0.473
cysH
Phosphoadenosine phosphosulfate reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily.
      
 0.456
ybeY
Conserved protein of unknown function, putative Metalloprotease; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
    
   0.448
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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