Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
gspEGeneral secretion pathway protein E; Function of strongly homologous gene; transporter. (577 aa)    
Predicted Functional Partners:
gspF
General secretion pathway protein F; Function of strongly homologous gene; transporter.
 
 
 0.982
pilC
Type IV pilus biogenesis protein PilC; Function of strongly homologous gene; transporter.
 
 0.953
gspG
General secretion pathway protein G; Function of homologous gene experimentally demonstrated in an other organism; transporter.
 
 
 0.943
pilD
Type IV pilus prepilin peptidase PilD; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue.
 
 
 0.942
NIDE2820
Homologs of previously reported genes of unknown function.
 
 
 0.928
NIDE2823
Protein of unknown function, putative Fimbrial assembly family; No homology to any previously reported sequences.
  
 
 0.871
NIDE2824
Protein of unknown function; No homology to any previously reported sequences.
  
 
 0.868
NIDE2830
Putative General secretion pathway protein D; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative membrane component.
 
  
 0.855
gspG3
General secretion pathway protein G; Function of strongly homologous gene; membrane component.
 
 
 0.846
NIDE2822
Homologs of previously reported genes of unknown function.
       0.817
Your Current Organism:
Nitrospira defluvii
NCBI taxonomy Id: 330214
Other names: Candidatus Nitrospira defluvii, LMG 27402, LMG:27402, N. defluvii, NCIMB 14950, strain A17
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